Sirius Pintuition^® – Moving from Localization to Surgical Marker Navigation

28 March 2023 – Eindhoven, Netherlands – Our portfolio company Sirius Medical, the leader in surgical marker navigation, today announced the successful closing of a Series B Round 12 M€. The funding will accelerate the worldwide growth of their product Pintuition and support further product development. Holland Capital acted as lead investor for this series B with support from existing investors BOM Brabant Ventures, Curie Capital, Team Holmium, and a major investment from Sirius Medical’s management and team. Norgine Ventures joined as a new investor in this round to support further commercial roll-out.

Sirius’ state-of-the-art navigation system Pintuition provides surgeons with real-time distance and directional navigational guidance to locate tumors easily and accurately. With over 100 active centers and more than 5,000 successful Pintuition procedures across Western Europe and the US, the company experienced an unprecedented growth in revenue in 2022, attributable to Pintuition’s ease of use, straightforward implementation, and its unmatched precision in locating the target tissue.

“Sirius Medical has done a great job developing and bringing to market the Pintuition technology with a strong commercial start”, says Peter Stein, Chief Executive of Norgine Ventures. “Norgine Ventures is excited to support Sirius Medical’s leadership and their vision to deliver cost effective solutions in surgery.”

“We are excited about the market potential for surgical marker navigation,” says Jan Frens van Giessel, partner at Holland Capital. “We believe that the Pintuition technology and its future innovations will significantly improve surgery of non-palpable tumors for patients, physicians and improve the care for cancer patients.” 

“Having become the fastest growing company in the industry is a clear confirmation of the unique benefits that our technology brings to both patients and physicians,” says Bram Schermers, CEO at Sirius Medical.  “Supported by this latest funding round I am confident that our highly talented and motivated team will further drive the adoption of Pintuition across the globe.”

About Sirius Medical

With its roots in the Netherlands Cancer Institute, Sirius Medical is dedicated to improving care for cancer patients by delivery of unsurpassed, yet affordable solutions that enable precise and efficient removal of tumors. The Pintuition technology is precise, simple, affordable and both CE marked, and FDA cleared.  Sirius Medical is rapidly expanding with over 100 centers and an international sales network in Europe and the USA. www.sirius-medical.com

About Holland Capital

Over the past 40 years Holland Capital has responsibly and successfully invested in more than 160 SMEs. With a clear investment strategy Holland Capital is active in the attractive growth markets of Healthcare and Technology. Holland Capital’s experienced, entrepreneurial and committed investment team aims to establish an open, sustainable and professional relationship with the companies it invests in with the common goal of achieving growth. Holland Capital is backed by a broad network of successful Healthcare and Technology entrepreneurs.

Do you want to step into the exciting world of Private Equity?

Holland Capital, an independent private equity firm with a focus on the Benelux & German mid-market, is looking for a full-time intern to join its buy-out team. Within 5 months, you will familiarize yourself with all aspects of the investment process to ramp up all skills related to PE investing.

Do you want to step into the exciting world of Venture Capital?

Holland Capital is looking for a full-time intern to join our VC team. Within 5 months, you will familiarize yourself
with all aspects of the investment process to ramp up all skills related to VC investing.

Do you want to step into the exciting world of Private Equity?

Holland Capital is an independent private equity firm focusing on technology and healthcare companies in the Benelux and DACH regions. For our team in Düsseldorf, we are looking for interns who want to actively accompany the investment process and gain in-depth knowledge in the field of private equity.

Interns in the investment team work as a recognized team member with the investment professionals and familiarize with the comprehensive private equity business. We are looking for interns to support the team in Düsseldorf, starting immediately and on an ongoing basis.

Amsterdam, 9^th of January 2023 – After a period of thorough preparation and refinement, the moment has arrived: our new consortium for digital transformation services launches its name: Emixa, accompanied by a new website and corporate identity. With Emixa, our portfolio companies Appronto, cards PLM Solutions, Dimensys, Magnus Digital and OnePLM have joined forces to complement one another’s services and provide customers with innovative, high-quality, and full-service solutions in the field of digital transformation. Placing a special focus on the manufacturing industry, also known as ‘Industry 4.0’, using Siemens, SAP, Mendix and other leading technologies.

Emixa is the only specialist that can realize the combination of Siemens/Mendix/SAP technology solutions. For clients this offers a unique one-stop shop that delivers the integrated solutions for next level digital transformation. Every industry has its own dynamics, with its own issues and challenges. Focussing on specific industries enables us to closely follow the trends and developments and to provide extra added value to companies in those markets. It is our ambition to make the most impact for our clients, as we already have been doing for decades within the technology consultancy firms part of Emixa.

Growth through a buy-and-build strategy

With the financial support of investor Holland Capital, Emixa is able to follow a buy-and-build strategy that allows the consortium to expand its business and service portfolio. The five companies that are united in Emixa employ a total of 420 people and focus on issues related to process optimisation, product lifecycle and asset management, IT architecture, low-code applications, system integrations, data analytics and change management. Emixa has the ambition to become one of the leading players in Western Europe and expand its established presence in Belgium, the Netherlands and the United Kingdom to the DACH region.

The companies that form Emixa will remain active under their own names and strive to grow their services related to digital transformation. Each in its own way, the companies united in Emixa make a major contribution to organisations in various sectors, such as: manufacturing, (online) retail, logistics, construction, infrastructure, financial services and education.

“The world is changing at a rapid pace. To remain competitive, companies have to choose a business model and complementary IT architecture that allow them to lead the way. Due to the powerful and unique combination of industry knowledge and technology expertise in the field of ERP, low-code applications, integrations and PLM solutions, we enable our customers to win in the challenging era of full-scale digitisation”, says Emixa CEO Peter-Jan Simons.

The companies behind Emixa

Emixa is a consortium that combines the knowledge, expertise and specialities of several renowned companies.

Appronto

Appronto was founded in 2013 in the Dutch city of Breda. The company focuses on the development of digital solutions for complex issues. Appronto is a specialist in the development of low-code solutions on the Mendix platform and in the realisation of system integrations via Boomi’s cloud integration platform. In 2021, Appronto became the first European Siemens Smart Expert Partner, received the Boomi Partner Spotlight Award and was chosen as Siemens’ Top Cloud Partner in the Benelux area.

cards PLM Solutions

cards PLM Solutions was founded in 1999 and has locations in Best (NL) and Genk (B). With a team of 56 professionals, the organisation specialises in the digitisation of business processes and information flows within the manufacturing industry. Many of the company’s customers are active in industries such as automotive, aerospace, high-tech machine building, medical devices, and consumer goods. Over the years, the company has developed into a specialised product lifecycle management (PLM) solutions provider. cards is a Siemens Platinum Expert Partner for Siemens Digital Industries Software.

Dimensys

Dimensys was founded in the year 2000 and helps companies achieve operational excellence in their business processes. Dimensys makes the life cycle of assets and products transparent, predictable and repeatable. This allows organisations to use assets more effectively. The company uses years of experience in the knowledge domains of asset and product lifecycle management, project and portfolio management, and supply chain management. Dimensys is a certified SAP Gold Partner, SAP Partner Center of Expertise and SAP Recognized Expertise Partner.

Magnus Digital

Magnus, founded in 1990, was the first SAP partner and one of the first Mendix partners in the Netherlands. Magnus Digital is an innovative IT and organisational consultancy agency that works with leading clients. Its portfolio contains a wide range of digital services, from advice to realisation. With approximately 100 consultants, it provides services related to digital transformation, data analytics, ERP implementations, and the development of low-code solutions. It also unburdens customers of the management of these solutions. Magnus Digital is active in retail, FMCG, wholesale, manufacturing, education, transport, construction, and several other industries.

OnePLM

OnePLM is one of the world’s largest Siemens Digital Industries Software Partners and the number one European Partner. The company has more than 25 years of industry experience and employs a team of 107 people. OnePLM provides PLM services and solutions to manufacturing companies in the UK and Ireland, both independent users and OEMs. In addition, OnePLM provides training, consultancy and support to a wide range of software customers.

Holland Capital

Over the past 40 years, Holland Capital has successfully invested in more than 150 Dutch SMEs. Using a clear, socially responsible and sustainable investment strategy, the company is active in the attractive growth markets of healthcare and technology. Holland Capital’s investment team seeks to build an open, sustainable and professional relationship with the management teams of the companies in which it invests, with the common goal of achieving sustainable growth.

Amsterdam, 16 december 2022 –  Holland Capital wint voor het derde jaar op rij de M&A Award in de categorie Best Venture & Growth Capital Provider.

Dit jaar was de investeerder twee maal genomineerd:

◾ Best Venture & Growth Capital Provider

◾ Best Small Cap Deal (Corius Group x Mauritskliniek)

M&A Awards

De M&A Awards is het jaarlijkse hoogtepunt voor de M&A-industrie met prestigieuze prijzen voor beste deals, adviseurs en investeerders. De afgelopen twee jaar won Holland Capital de award in de categorie ‘Best Venture & Growth Capital Provider’. In 2018 was ze winnaar in de categorie ‘Best Small Cap Deal’ met de deal KPN – QSight IT. Het event vindt jaarlijks plaats in de Beurs van Berlage.

Over Holland Capital

Holland Capital heeft in de afgelopen 40 jaar op een verantwoorde en succesvolle wijze in meer dan 150 Nederlandse MKB-ondernemingen geïnvesteerd. Met een heldere investeringsstrategie is zij actief in de aantrekkelijke groeimarkten Healthcare en Technology. Het ervaren en betrokken investeringsteam weet wat ondernemen is. Ze streeft naar een open, duurzame en professionele relatie met managementteams van de bedrijven waar zij in investeert, met het gezamenlijke doel om groei te realiseren. Holland Capital wordt ondersteund door een breed netwerk aan succesvolle ondernemers in Healthcare en Technology.

Amsterdam, 2 december 2022 –  Holland Capital investeert in Cuccibu en QSN, twee gerenommeerde spelers op het vlak van risicomanagement met een focus op Privacy en Security consultancy. De investering van Holland Capital zorgt er voor dat de ambitieuze groeiambities gerealiseerd kunnen worden.

Privacy en security consultancy

Digitalisering binnen organisaties, toenemende wet- en regelgeving en de groei van het aantal cyber aanvallen zorgen ervoor dat risico management een enorme vlucht maakt. Cuccibu en QSN ontwikkelen, implementeren en beheren op maat gemaakte risico management systemen voor klanten binnen diverse categorieën zoals privacy, informatiebeveiliging, cyber security, kwaliteitsmanagement, arbo veiligheid en duurzaamheid.

Krachtenbundeling

Door de krachtenbundeling ontstaat een uitgebreid dienstenaanbod waarmee zowel publieke als commerciële klanten volledig kunnen worden bediend. Daarnaast biedt de samenwerking medewerkers de kans zich breder te ontwikkelen. Gezamenlijk kunnen beide bedrijven een nog belangrijkere rol spelen in deze sterk groeiende en jonge markt.

Verspreid over kantoren in Eindhoven, Delft en Sassenheim hebben de bedrijven ruim 90 medewerkers in dienst. Het huidige management en de oprichters van beide bedrijven blijven actief betrokken.

Tim Florack, CEO Cuccibu: “We zijn niet over één nacht ijs gegaan bij de keuze voor een partij, waarbij het geloof in een krachtige samenwerking op basis van onze kernwaarden doorslaggevend is geweest. Holland Capital biedt ons de mogelijkheid om de Cuccibu propositie te verstevigen en onze ambities te verwezenlijken. Voor onze collega’s betekent deze stap meer mogelijkheden voor ontwikkeling, terwijl onze klanten een sterker dienstenportfolio mogen verwachten”.

Nicolette en Ron Wijling, oprichters en directie QSN: “Om verder te kunnen groeien had QSN een sterke partner nodig, die hebben we gevonden in Cuccibu omdat zij zich verder wilden ontwikkelen op onze vakgebieden, daarmee was één plus één drie!”

Hubert Verbeek, managing partner Holland Capital, “Cuccibu en QSN zijn spelers die voorop lopen in de markt van risico management. Door de krachtenbundeling kunnen de bedrijven versneld groeien en hun leidende positie in deze nog jonge markt verder uitbouwen. We zijn enthousiast om de managementteams te ondersteunen bij het realiseren van hun groeiplannen”.

Over Cuccibu

Cuccibu, opgericht in 2014, heeft in de afgelopen 8 jaar een sterke naam opgebouwd in de wereld van informatiebeveiliging, cyber security en privacy consultancy. Met kantoren in Eindhoven en Delft is Cuccibu een gerenommeerde partij die hoofdzakelijk actief is in de publieke sector (overheid, zorg en onderwijs).

Over QSN

QSN, opgericht in 1997, heeft een sterke naam opgebouwd met dienstverlening op het gebied van informatiebeveiliging en diverse andere risico management gebieden zoals kwaliteitsmanagement, arbo veiligheid en duurzaamheid. Vanuit het kantoor in Sassenheim bedient zij voornamelijk de Nederlandse commerciële markt.

Over Holland Capital

Holland Capital heeft in de afgelopen 40 jaar op een verantwoorde en succesvolle wijze in meer dan 150 Nederlandse MKB-ondernemingen geïnvesteerd. Met een heldere investeringsstrategie is zij actief in de aantrekkelijke groeimarkten Healthcare en Technology. Het ervaren en betrokken investeringsteam weet wat ondernemen is. Ze streeft naar een open, duurzame en professionele relatie met managementteams van de bedrijven waar zij in investeert, met het gezamenlijke doel om groei te realiseren. Holland Capital wordt ondersteund door een breed netwerk aan succesvolle ondernemers in Healthcare en Technology.

Amsterdam, 15 November 2022 – Teledyne DALSA, a Teledyne Technologies company and global leader in Digital X-Ray Image Sensing technology, is pleased to announce it has acquired the Sigmascreening B.V. patents and IP portfolio on pressure-sensitive breast compression for screening. With its purchase, Teledyne DALSA has exclusive access to the Sigmascreening IP portfolio and algorithms. Holland Capital was one of the early investors in Sigmascreening.

Unique combination

The unique combination of detector and pressure-sensitive compression is expected to create new possibilities for immediate diagnostic information as well as biomarkers for breast screening. According to Thorsten Achterkirchen, Vice President and General Manager of Teledyne DALSA’s X-Ray Solutions business, “We intend to expand our CMOS X-Ray detector product line for mammography and digital breast tomosynthesis (DBT) with new subsystem products for optimizing breast imaging and improving patient comfort during mammographic screening.”

Ivo Aarninkhof, CEO of Sigmascreening, says that ‘’We are delighted with the purchase of the Sigmascreening patents and IP portfolio by Teledyne DALSA. Use of the pressure-based compression during digital breast tomosynthesis and mammography improves participant and technologist experience and reduces compression pressure variability, mean breast thickness, and glandular dose.”¹

Expertise in radiology

Holland Capital joined the company in 2014 as an early investor. The investment has been used for product development and commercial growth in recent years. Holland Capital is experienced in supporting innovative radiology solutions. This is the investor’s second exit in the field of medical imaging, following the acquisition of Quantib, a leading radiology artificial intelligence (“AI”) company, by RadNet Inc earlier this year.

Jan-Frens van Giessel, Partner Holland Capital : “We are proud that we have been able to assist Sigmascreening in the past 8 years. Sigmascreening’s pressure sensitive breast compression reduces extreme pain during mammography and improves detection of breast cancer. It is great to see that this important healthcare innovation will become available for women worldwide with the acquisition of Teledyne DALSA.”

About Teledyne DALSA

Teledyne DALSA provides state-of-the-art image sensing, capture and processing solutions to medical, dental, and scientific equipment manufacturers. Building on more than 30 years of proven capability and innovation, our highly skilled team of imaging specialists adds value with their continued focus on leading-edge product design. Our manufacturing processes are tailored to comply with the stringent quality, reliability, and traceability requirements of the medical and scientific X-ray community.

About Sigmascreening

Sigmascreening B.V. is a medical device company focusing on the development of new innovative products in the area of digital mammography and breast cancer screening. Sigmascreening was established as a spin-off company from the Amsterdam UMC.

About Holland Capital

Over the past 40 years, Holland Capital has responsibly and successfully invested in over more than 150 SME-companies. With a clear investment strategy Holland Capital is active in the attractive growth markets of Healthcare and Technology. Holland Capital’s experienced and committed investment team understand entrepreneurship. They aim to establish an open, sustainable, and professional relationship with the companies they invest in, with the common goal of achieving growth. Holland Capital is backed by a broad network of successful Healthcare and Technology entrepreneurs.

¹ quote is based on this scientific article: https://academic.oup.com/jbi/advance-article/doi/10.1093/jbi/wbaa070/5902745